A self-assembled cage as a non-covalent protective group: regioselectivity control in the nucleophilic substitution of aryl-substituted allylic chlorides.
نویسندگان
چکیده
Aryl-substituted allylic chlorides are accommodated by a self-assembled cage in such a restricted orientation that the internal reaction sites are shielded while the external ones are exposed. This non-covalent protection enhances terminal regioselectivity in the allylic substitution.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 63 شماره
صفحات -
تاریخ انتشار 2012